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Objective To study the medication rule of traditional Chinese medicine treatment of urinary stone disease data mining. Methods Clinical study literature in China Journal Full-text Database 1985-2012 on Chinese medicine prescription of urinary stone disease were retrieved, database was established and analyzed by SPSS12.0 statistical software. Results There were 209 literatures meeting the inclusion criteria of Chinese medicine for urinary lithiasis, including 209 oral administration compound, 234 kinds of traditional Chinese medicine, 1843 times of frequency. The traditional Chinese medicine mainly for diuresis and diffusing dampness, restoring vital energy, blood-activating and removing stasis, regulating qi, clearing heat, promoting digestion and purgation, counted for 86.43%;with flavour of sweet, bitter, spicy, fresh, counted for 86.67%;nature of cold, plain, warm, counted for 93.08%;meridian tropism of liver, bladder, spleen, stomach, kidney, lung, heart, counted for 83.67%. Conclusion Trditional Chinese medicine of diuresis and diffusing dampness, restoring vital energy, blood-activating and removing stasis, regulating qi, clearing heat were commonly used. The core single medicine are Lysimachiae Herba, Glycyrrhizae Radix, Talcum, Lygodii Spora, Plantaginis Semen, Pyrrosiae Folium, Cyathulae Radix, Malvae Fructus, Galli Gigerii Endothelium Corneum, Akebiae caulis, etc.
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Objective To evaluate the sufentanil-sparing effect of ketorolac tromethamine for postoperative analgesia in the elderly patients.Methods Sixty ASA Ⅱ or Ⅲ patients,aged ≥ 65 yr,with a body mass index of 18-24 kg/m2,undergoing elective gynecological operations,were randomly divided into 2 groups(n =30 each):sufentanil group(group S)and ketorolac tromethamine plus sufentanil group(group T).Both groups received combined intravenous-inhalational anesthesia and patient-controlled intravenous analgesia(PCIA)after operation.PCIA solution contained ketorolac tromethamine 180 mg and sufentanil 100 μg in 100 ml of normal saline in group T.After a loading dose of ketorolac tromethamine 30 mg was injected intravenously at 15 min before the end of operation,the PCA pump was set up with a 1.6 ml bolus dose,a 20 rain lockout interval and background infusion at a rate of 1.5 ml/h in group T.PCIA solution contained sufentanil 100 μg in 100 ml of normal saline in group S.After a loading dose of sufentanil 5 μg was injected intravenously at 15 min before the end of operation,the PCA pump was set up with a 1.6 ml bolus dose,a 20 min lockout interval and background infusion at a rate of 1.5 ml/h in group S.The effective analgesia(postoperative VAS scores at rest and during activity ＜ 3)was maintained within 48 h after operation.The amount of sufentanil consumed within 48 h after operation and adverse effects were recorded.Results Compared with group S,the amount of sufentanil consumed within 48 h after operation was significantly reduced,and the incidence of nausea and vomiting,urinary retention and pruritus was significantly decreased in group T(P ＜ 0.05).Conclusion Ketorolac tromethamine used with PCIA with sufenlanil has a significant sufentanil-sparing effecl for posloperative analgesia and improves the safety of analgesia in the elderly patients.
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Objective To observe the effect and safety of acupuncture treatment on refractory auditory hallucination in schizophrenia patients. Methods The 100 patients clinically diagnosed as refractory auditory hallucination of schizophrenia were randomized into test group and control group with 50 in each. The control group was treated with risperidone alone while the test group was treated with acupuncture on the basis of TCM syndrome differentiation in addition to risperidone. One month was one course,totally 3 courses of treatment was given. The clinical effect of both groups was observed. The effect in different courses of disease and the effect in different syndromes of the test group were compared respectively. Before and after treatment the brief psychiatric rating scale (BPRS),specific auditory hallucination scale(SAHS),and treatment emergent symptom scale (TESS) were adopted to score the patients of both groups. Results In the test group,there were 3 cases lost,the total effective rate was 72.34%; while in the control group,there was 1 case lost,the total effective rate was 38.78%,the difference being significant (P 0.05). The difference in BPRS and SHRS scores at the same period of time after 2nd and 3rd courses of treatment of the two groups was significant (P